Once deeply trusted in the 1899 Merck Manual, natural medicine reigned supreme—so why was it erased? Uncover the forgotten history of healing and the forces that sidelined it.
What a find! I wish I could get my hands on one of these! As a former pharmacy technician and team leader, ther Merck Manual was our go to. Now that I am a farmer I have the veterinary volume.
Thank you Thank you . so interesting ! I got my first PDR from a nurse friend , after reading that , I started buying my own . But I was amazed that they would RX drugs so dangerous . Because of my youth I still trusted doctors back then , It took a few decades before I could see the truth . I am loath to even see a AMA doctor today .They don't know anything , outside of their protocol and opinion .
Papaya extract, specifically the enzyme papain, has shown promising effects in combating biofilm-forming antibiotic-resistant bacteria. Here are some key findings:
* **Papain Enzyme**: Papain, a cysteine protease isolated from the papaya fruit (*Carica papaya*), has been studied for its antibiofilm activity. It has been found to inhibit biofilm formation and disrupt existing biofilms in drug-resistant bacteria such as *Klebsiella pneumoniae* Papain can also reduce the viability of biofilms formed by *Staphylococcus aureus* and *Campylobacter jejuni*
* **Mechanism of Action**: Papain works by degrading the extracellular polymeric substances (EPS) that make up the biofilm matrix, including exopolysaccharides and proteins. This degradation increases the permeability of the biofilm, making the bacteria more susceptible to antimicrobial treatments
* **Applications**: Papain has been immobilized on various polymers, such as low-density polyethylene (LDPE), high-density polyethylene (HDPE), linear low-density polyethylene (LLDPE), and polycaprolactam (PCL), to create antimicrobial food packaging. These materials have shown significant antibiofilm properties, particularly against *Acinetobacter* spp. and *Staphylococcus aureus*
* **Fermented Papaya Preparation (FPP)**: Fermented papaya preparation (FPP) has been investigated for its potential in improving oral health, particularly in diabetics. FPP has shown inhibitory effects on the growth, hydrophobicity, and acid production of common oral pathogens such as *Streptococcus mutans*, *Streptococcus mitis*, and *Lactobacillus acidophilus*
* **Antibiotic Resistance in Biofilms**: Biofilms are known to favor the rapid evolution of antibiotic resistance. Studies have shown that mutations in genes like *sbmA* and *fusA* are rapidly selected in biofilm-forming *Escherichia coli* when exposed to intermittent antibiotic treatments, highlighting the need for alternative strategies like the use of papain to combat biofilm-associated infections
These findings suggest that papain and papaya extracts could be valuable tools in the fight against antibiotic-resistant bacteria, particularly in the context of biofilm-related infections.
The 1899 Merck Manual is also available through the Internet Archive in several forms including PDF which I prefer. I find it terribly sad that osteopaths, naturopaths and herbalists were nearly completely wiped out in the 20th century by Rockefeller funded medical schools and the petroleum based "medicines" they promoted. All this was manipulated to enrich the Rockefeller family. Just consider annual deaths due to prescribed medicines, over 106,000 deaths annually among hospitalized patients alone, not counting opioid overdose -- OBSCENE!
My great grandfather created a pharmaceutical distribution company that he operated for over forty years. It's still in existence today, but not owned by our family. I've often wondered, especially recently, what he distributed and what he would think of medicine as practiced today.
Back during prohibition, pharmacists became popular for their "health" sodas, sometimes made with lithium and coca. This started the whole soda market we have today. The sodas were a mix of herbs, syrups, powders, and carbonated water. Eventually, the only stimulant allowed was caffeine. There were calls for that practice to be ended, too. But, there was an outcry from the workers who drank it for the energy kick, so it was allowed to continue.
What a find! I wish I could get my hands on one of these! As a former pharmacy technician and team leader, ther Merck Manual was our go to. Now that I am a farmer I have the veterinary volume.
The Gutenberg press free version is linked above : )
Thank you Thank you . so interesting ! I got my first PDR from a nurse friend , after reading that , I started buying my own . But I was amazed that they would RX drugs so dangerous . Because of my youth I still trusted doctors back then , It took a few decades before I could see the truth . I am loath to even see a AMA doctor today .They don't know anything , outside of their protocol and opinion .
Papaya extract, specifically the enzyme papain, has shown promising effects in combating biofilm-forming antibiotic-resistant bacteria. Here are some key findings:
* **Papain Enzyme**: Papain, a cysteine protease isolated from the papaya fruit (*Carica papaya*), has been studied for its antibiofilm activity. It has been found to inhibit biofilm formation and disrupt existing biofilms in drug-resistant bacteria such as *Klebsiella pneumoniae* Papain can also reduce the viability of biofilms formed by *Staphylococcus aureus* and *Campylobacter jejuni*
* **Mechanism of Action**: Papain works by degrading the extracellular polymeric substances (EPS) that make up the biofilm matrix, including exopolysaccharides and proteins. This degradation increases the permeability of the biofilm, making the bacteria more susceptible to antimicrobial treatments
* **Applications**: Papain has been immobilized on various polymers, such as low-density polyethylene (LDPE), high-density polyethylene (HDPE), linear low-density polyethylene (LLDPE), and polycaprolactam (PCL), to create antimicrobial food packaging. These materials have shown significant antibiofilm properties, particularly against *Acinetobacter* spp. and *Staphylococcus aureus*
* **Fermented Papaya Preparation (FPP)**: Fermented papaya preparation (FPP) has been investigated for its potential in improving oral health, particularly in diabetics. FPP has shown inhibitory effects on the growth, hydrophobicity, and acid production of common oral pathogens such as *Streptococcus mutans*, *Streptococcus mitis*, and *Lactobacillus acidophilus*
* **Antibiotic Resistance in Biofilms**: Biofilms are known to favor the rapid evolution of antibiotic resistance. Studies have shown that mutations in genes like *sbmA* and *fusA* are rapidly selected in biofilm-forming *Escherichia coli* when exposed to intermittent antibiotic treatments, highlighting the need for alternative strategies like the use of papain to combat biofilm-associated infections
These findings suggest that papain and papaya extracts could be valuable tools in the fight against antibiotic-resistant bacteria, particularly in the context of biofilm-related infections.
The 1899 Merck Manual is also available through the Internet Archive in several forms including PDF which I prefer. I find it terribly sad that osteopaths, naturopaths and herbalists were nearly completely wiped out in the 20th century by Rockefeller funded medical schools and the petroleum based "medicines" they promoted. All this was manipulated to enrich the Rockefeller family. Just consider annual deaths due to prescribed medicines, over 106,000 deaths annually among hospitalized patients alone, not counting opioid overdose -- OBSCENE!
My great grandfather created a pharmaceutical distribution company that he operated for over forty years. It's still in existence today, but not owned by our family. I've often wondered, especially recently, what he distributed and what he would think of medicine as practiced today.
Back during prohibition, pharmacists became popular for their "health" sodas, sometimes made with lithium and coca. This started the whole soda market we have today. The sodas were a mix of herbs, syrups, powders, and carbonated water. Eventually, the only stimulant allowed was caffeine. There were calls for that practice to be ended, too. But, there was an outcry from the workers who drank it for the energy kick, so it was allowed to continue.
Thank you for this very important article!